Lack of microsatellite instability in gastrointestinal stromal tumors

The microsatellite instability (MSI) phenotype may constitute an important biomarker for patient response to immunotherapy, particularly to anti-programmed death-1 inhibitors. MSI is a type of genomic instability caused by a defect in DNA mismatch repair (MMR) proteins, which is present mainly in co...

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Udgivet i:Oncol Lett
Main Authors: Campanella, Nathália C., Scapulatempo-Neto, Cristovam, Abrahão-Machado, Lucas Faria, Torres De Oliveira, Antônio Talvane, Berardinelli, Gustavo N., Guimarães, Denise Peixoto, Reis, Rui M.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662911/
https://ncbi.nlm.nih.gov/pubmed/29113157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6884
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