Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs)

Somatic mutations in the promoter region of telomerase reverse transcriptase (TERT) gene, mainly at positions c.−124 and c.−146 bp, are frequent in several human cancers; yet its presence in gastrointestinal stromal tumor (GIST) has not been reported to date. Herein, we searched for the presence and...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Campanella, Nathália C, Celestino, Ricardo, Pestana, Ana, Scapulatempo-Neto, Cristovam, de Oliveira, Antonio Talvane, Brito, Maria José, Gouveia, António, Lopes, José Manuel, Guimarães, Denise Peixoto, Soares, Paula, Reis, Rui M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795049/
https://ncbi.nlm.nih.gov/pubmed/25248398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.195
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