Human Primary Macrophages Derived In Vitro from Circulating Monocytes Comprise Adherent and Non-Adherent Subsets with Differential Expression of Siglec-1 and CD4 and Permissiveness to HIV-1 Infection

Macrophages are a major target for human immunodeficiency virus type 1 (HIV-1) infection. However, macrophages are largely heterogeneous and may exhibit differences in permissiveness to HIV-1 infection. This study highlights the interplay of macrophage heterogeneity in HIV-1 pathogenesis. We show th...

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Publicat a:Front Immunol
Autors principals: Jobe, Ousman, Kim, Jiae, Tycksen, Eric, Onkar, Sayali, Michael, Nelson L., Alving, Carl R., Rao, Mangala
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662875/
https://ncbi.nlm.nih.gov/pubmed/29123518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01352
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