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Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia
Chronic inflammation is a hallmark of cystic fibrosis (CF) and associated with increased production of transforming growth factor (TGF) β and interleukin (IL)-8. α-klotho (KL), a transmembrane or soluble protein, functions as a co-receptor for Fibroblast Growth Factor (FGF) 23, a known pro-inflammat...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5662572/ https://ncbi.nlm.nih.gov/pubmed/29085059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14811-0 |
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