Production of bioactive liver-targeting interferon Mu-IFN-CSP by soluble prokaryotic expression

A novel liver-targeting interferon (IFN-CSP) was successfully over-expressed in our previous work. The in vitro and in vivo investigation revealed that IFN-CSP has significant anti-hepatitis B virus (HBV) effect and liver-targeting capacity. However, due to the IFN-CSP tends to form inclusion bodies...

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Bibliographische Detailangaben
Veröffentlicht in:AMB Express
Hauptverfasser: Liu, Along, Gui, Shuiqing, Zhang, Lun, Chen, Zhaoxia, Tang, Yanan, Xiao, Mingzhu, Wang, Jie, Liu, Wenbin, Jin, Xiaobao, Zhu, Jiayong, Lu, Xuemei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662524/
https://ncbi.nlm.nih.gov/pubmed/29086199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-017-0493-z
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