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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers

Flow of fluids through the gut, such as milk from a neonatal diet, generates a shear stress on the unilaminar epithelium lining the lumen. We report that exposure to physiological levels of fluid shear stress leads to the formation of large vacuoles, containing extracellular contents within polarizi...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Kim, Sun Wook, Ehrman, Jonathan, Ahn, Mok-Ryeon, Kondo, Jumpei, Lopez, Andrea A. Mancheno, Oh, Yun Sik, Kim, Xander H., Crawley, Scott W., Goldenring, James R., Tyska, Matthew J., Rericha, Erin C., Lau, Ken S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662261/
https://ncbi.nlm.nih.gov/pubmed/28855375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0021
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