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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers

Flow of fluids through the gut, such as milk from a neonatal diet, generates a shear stress on the unilaminar epithelium lining the lumen. We report that exposure to physiological levels of fluid shear stress leads to the formation of large vacuoles, containing extracellular contents within polarizi...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Main Authors: Kim, Sun Wook, Ehrman, Jonathan, Ahn, Mok-Ryeon, Kondo, Jumpei, Lopez, Andrea A. Mancheno, Oh, Yun Sik, Kim, Xander H., Crawley, Scott W., Goldenring, James R., Tyska, Matthew J., Rericha, Erin C., Lau, Ken S.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662261/
https://ncbi.nlm.nih.gov/pubmed/28855375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0021
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