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Mellitate: A multivalent anion with extreme charge density causes rapid aggregation and misfolding of wild type lysozyme at neutral pH

Due to its symmetric structure and abundance of carboxyl groups, mellitic acid (MA–benzenehexacarboxylic acid) has an uncommon capacity to form highly ordered molecular networks. Dissolved in water, MA dissociates to yield various mellitate anions with pronounced tendencies to form complexes with ca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ścibisz, Grzegorz, Dec, Robert, Dzwolak, Wojciech
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662172/
https://ncbi.nlm.nih.gov/pubmed/29084264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187328
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