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Mellitate: A multivalent anion with extreme charge density causes rapid aggregation and misfolding of wild type lysozyme at neutral pH

Due to its symmetric structure and abundance of carboxyl groups, mellitic acid (MA–benzenehexacarboxylic acid) has an uncommon capacity to form highly ordered molecular networks. Dissolved in water, MA dissociates to yield various mellitate anions with pronounced tendencies to form complexes with ca...

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Vydáno v:PLoS One
Hlavní autoři: Ścibisz, Grzegorz, Dec, Robert, Dzwolak, Wojciech
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662172/
https://ncbi.nlm.nih.gov/pubmed/29084264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187328
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