The IRF4 gene regulatory module functions as a read-write integrator to dynamically coordinate T helper cell fate

Transcriptional regulation during CD4(+) T cell fate decisions enables their differentiation into distinct states, guiding immune responses towards antibody production via Tfh cells or inflammation by Teff cells. Tfh–Teff fate commitment is regulated by mutual antagonism between the transcription fa...

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Detaylı Bibliyografya
Yayımlandı:Immunity
Asıl Yazarlar: Krishnamoorthy, Veena, Kannanganat, Sunil, Maienschein-Cline, Mark, Cook, Sarah L., Chen, Jianjun, Bahroos, Neil, Sievert, Evelyn, Corse, Emily, Chong, Anita, Sciammas, Roger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661949/
https://ncbi.nlm.nih.gov/pubmed/28930660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.09.001
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