Therapeutic potential of an anti-HER2 single chain antibody–DM1 conjugates for the treatment of HER2-positive cancer

Antibody–drug conjugates (ADCs) take the advantage of monoclonal antibodies to selectively deliver highly potent cytotoxic drugs to tumor cells, which have become a powerful measure for cancer treatment in recent years. To develop a more effective therapy for human epidermal growth factor receptor 2...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Zhang, Hang, Wang, Yuxi, Wu, Yangping, Jiang, Xiaohua, Tao, Yiran, Yao, Yuqin, Peng, Yujia, Chen, Xiangzheng, Fu, Yuyin, Yu, Lin, Wang, Ruixue, Lai, Qinhuai, Lai, Weirong, Li, Wenting, Kang, Yuhuan, Yi, Shuli, Lu, Ying, Gou, Lantu, Wu, Min, Yang, Jinliang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661626/
https://ncbi.nlm.nih.gov/pubmed/29263918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2017.15
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