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Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome

Pancreatic ductal adenocarcinoma (PDAC) is a tumor with a poor prognosis, and no targeted therapy is currently available. The aim of the present study was to investigate the prognostic significance of the expression of V-Ki-ras2 Κirsten rat sarcoma viral oncogene homolog (KRAS), downstream signaling...

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Pubblicato in:Oncol Lett
Autori principali: Lemstrova, Radmila, Brynychova, Veronika, Hughes, David J., Hlavac, Viktor, Dvorak, Pavel, Doherty, Joanne E., Murray, Helena A., Crockard, Martin, Oliverius, Martin, Hlavsa, Jan, Honsova, Eva, Mazanec, Jan, Kala, Zdenek, Lovecek, Martin, Havlik, Roman, Ehrmann, Jiri, Strouhal, Ondrej, Soucek, Pavel, Melichar, Bohuslav, Mohelnikova-Duchonova, Beatrice
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661609/
https://ncbi.nlm.nih.gov/pubmed/29113235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6946
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