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FOLFOX/FOLFIRI pharmacogenetics: The call for a personalized approach in colorectal cancer therapy

While 5-fluorouracil used as single agent in patients with metastatic colorectal cancer has an objective response rate around 20%, the administration of combinations of irinotecan with 5-fluorouracil/folinic acid or oxaliplatin with 5-fluorouracil/folinic acid results in significantly increased resp...

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Detalhes bibliográficos
Main Authors: Mohelnikova-Duchonova, Beatrice, Melichar, Bohuslav, Soucek, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130839/
https://ncbi.nlm.nih.gov/pubmed/25132748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i30.10316
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