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A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence
At their proliferative limit, normal cells arrest and undergo replicative senescence, displaying large cell size, flat morphology, and senescence-associated beta-galactosidase (SA-β-Gal) activity. Normal or tumor cells exposed to genotoxic stress undergo therapy-induced senescence (TIS), displaying...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661608/ https://ncbi.nlm.nih.gov/pubmed/29090099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2017.75 |
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