Combination of calcineurin B subunit (CnB) and 5-fluorouracil reverses 5-fluorouracil-induced immunosuppressive effect and enhances the antitumor activity in hepatocellular carcinoma

Five-fluorouracil (5-FU) is a widely used chemotherapeutic agent for digestive system tumors; however, continuous use of 5-FU may cause severe side effects, including myelosuppression and immunosuppression. Our previous study revealed that calcineurin B subunit (CnB), an innovative genetic engineeri...

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Publicado en:Oncol Lett
Autores principales: Zhang, Wenlong, Zhong, Youxiu, Cui, Hongfei, Wang, Liya, Yang, Rui, Su, Zhenyi, Xiang, Benqiong, Wei, Qun
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661471/
https://ncbi.nlm.nih.gov/pubmed/29113258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6958
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