The Loss of GSTM1 Associates with Kidney Failure and Heart Failure

Glutathione S-transferase mu 1 (GSTM1) encodes an enzyme that catalyzes the conjugation of electrophilic compounds with glutathione to facilitate their degradation or excretion. The loss of one or both copies of GSTM1 is common in many populations and has been associated with CKD progression. With t...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Tin, Adrienne, Scharpf, Robert, Estrella, Michelle M., Yu, Bing, Grove, Megan L., Chang, Patricia P., Matsushita, Kunihiro, Köttgen, Anna, Arking, Dan E., Boerwinkle, Eric, Le, Thu H., Coresh, Josef, Grams, Morgan E.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2017
Sujets:
Clinical Epidemiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661294/
https://ncbi.nlm.nih.gov/pubmed/28720685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030228
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