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PTEN inhibits replicative senescence‐induced MMP‐1 expression by regulating NOX4‐mediated ROS in human dermal fibroblasts

The biological function of NADPH oxidase (NOX) is the generation of reactive oxygen species (ROS). ROS, primarily arising from oxidative cell metabolism, play a major role in both chronological ageing and photoageing. ROS in extrinsic and intrinsic skin ageing may be assumed to induce the expression...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Noh, Eun‐Mi, Kim, Jeong‐Mi, Hong, On‐Yu, Song, Hyun‐Kyung, Kim, Jong‐Suk, Kwon, Kang‐Beom, Lee, Young‐Rae
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661253/
https://ncbi.nlm.nih.gov/pubmed/28557373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13220
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