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Apoptotic Cells Induced Signaling for Immune Homeostasis in Macrophages and Dendritic Cells

Inefficient and abnormal clearance of apoptotic cells (efferocytosis) contributes to systemic autoimmune disease in humans and mice, and inefficient chromosomal DNA degradation by DNAse II leads to systemic polyarthritis and a cytokine storm. By contrast, efficient clearance allows immune homeostasi...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Trahtemberg, Uriel, Mevorach, Dror
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661053/
https://ncbi.nlm.nih.gov/pubmed/29118755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01356
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