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Apoptotic Cells Induced Signaling for Immune Homeostasis in Macrophages and Dendritic Cells
Inefficient and abnormal clearance of apoptotic cells (efferocytosis) contributes to systemic autoimmune disease in humans and mice, and inefficient chromosomal DNA degradation by DNAse II leads to systemic polyarthritis and a cytokine storm. By contrast, efficient clearance allows immune homeostasi...
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| Udgivet i: | Front Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661053/ https://ncbi.nlm.nih.gov/pubmed/29118755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01356 |
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