Thrombospondin-1-N-Terminal Domain Induces a Phagocytic State and Thrombospondin-1-C-Terminal Domain Induces a Tolerizing Phenotype in Dendritic Cells

In our previous study, we have found that thrombospondin-1 (TSP-1) is synthesized de novo upon monocyte and neutrophil apoptosis, leading to a phagocytic and tolerizing phenotype of dendritic cells (DC), even prior to DC-apoptotic cell interaction. Interestingly, we were able to show that heparin bi...

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Detalhes bibliográficos
Main Authors: Tabib, Adi, Krispin, Alon, Trahtemberg, Uriel, Verbovetski, Inna, Lebendiker, Mario, Danieli, Tsafi, Mevorach, Dror
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733053/
https://ncbi.nlm.nih.gov/pubmed/19721725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006840
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