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ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA
DNA gyrase is a molecular motor that harnesses the free energy of ATP hydrolysis to introduce negative supercoils into DNA. A critical step in this reaction is the formation of a chiral DNA wrap on a similar scale to the nucleosome. Here we observe gyrase structural dynamics using a single-molecule...
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| 發表在: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660678/ https://ncbi.nlm.nih.gov/pubmed/22484318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2278 |
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