Functional and structural consequences of chemokine (C-X-C motif) receptor 4 activation with cognate and non-cognate agonists

Chemokine (C-X-C motif) receptor 4 (CXCR4) regulates cell trafficking and plays important roles in the immune system. Ubiquitin has recently been identified as an endogenous non-cognate agonist of CXCR4, which activates CXCR4 via interaction sites that are distinct from those of the cognate agonist...

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Veröffentlicht in:Mol Cell Biochem
Hauptverfasser: Eby, Jonathan M., Abdelkarim, Hazem, Albee, Lauren J., Tripathi, Abhishek, Gao, Xianlong, Volkman, Brian F., Gaponenko, Vadim, Majetschak, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660673/
https://ncbi.nlm.nih.gov/pubmed/28455789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-3044-7
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