Inherited Chromosomally Integrated Human Herpesvirus 6 Genomes Are Ancient, Intact, and Potentially Able To Reactivate from Telomeres

The genomes of human herpesvirus 6A (HHV-6A) and HHV-6B have the capacity to integrate into telomeres, the essential capping structures of chromosomes that play roles in cancer and ageing. About 1% of people worldwide are carriers of chromosomally integrated HHV-6 (ciHHV-6), which is inherited as a...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Zhang, Enjie, Bell, Adam J., Wilkie, Gavin S., Suárez, Nicolás M., Batini, Chiara, Veal, Colin D., Armendáriz-Castillo, Isaac, Neumann, Rita, Cotton, Victoria E., Huang, Yan, Porteous, David J., Jarrett, Ruth F., Davison, Andrew J., Royle, Nicola J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Genetic Diversity and Evolution
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660504/
https://ncbi.nlm.nih.gov/pubmed/28835501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01137-17
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