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Lysine 242 within Helix 10 of the Pseudorabies Virus Nuclear Egress Complex pUL31 Component Is Critical for Primary Envelopment of Nucleocapsids

Newly assembled herpesvirus nucleocapsids are translocated from the nucleus to the cytosol by a vesicle-mediated process engaging the nuclear membranes. This transport is governed by the conserved nuclear egress complex (NEC), consisting of the alphaherpesviral pUL34 and pUL31 homologs. The NEC is n...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rönfeldt, Sebastian, Klupp, Barbara G., Franzke, Kati, Mettenleiter, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660471/
https://ncbi.nlm.nih.gov/pubmed/28878082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01182-17
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