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Identification of Conserved Amino Acids in pUL34 Which Are Critical for Function of the Pseudorabies Virus Nuclear Egress Complex

Nuclear egress of herpesvirus capsids is mediated by a conserved heterodimeric complex of two viral proteins, designated pUL34 and pUL31 in herpes simplex virus and pseudorabies virus (PrV). pUL34, a tail-anchored membrane protein, is targeted to the nuclear envelope and recruits pUL31 to the inner...

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Autors principals: Paßvogel, Lars, Janke, Una, Klupp, Barbara G., Granzow, Harald, Mettenleiter, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093891/
https://ncbi.nlm.nih.gov/pubmed/24648464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00595-14
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