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RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer

Elevated lipid metabolism promotes cancer cell proliferation. Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancers, characterized by ectopic lipid accumulation. However, the relationship between aberrant lipid metabolism and tumorigenesis in ccRCC is not thoroughly un...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Lee, Jae Ho, Jeon, Yong Geun, Lee, Kyoung-Hwa, Lee, Hye Won, Park, Jeu, Jang, Hagoon, Kang, Minyong, Lee, Hye Sun, Cho, Hee Jin, Nam, Do-Hyun, Kwak, Cheol, Kim, Jae Bum
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660462/
https://ncbi.nlm.nih.gov/pubmed/28827316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00265-17
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