Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives

The Melanoma-associated Antigen gene family (MAGE) generally encodes for tumour antigens. We had identified that one of the MAGE gene members, Mageb16 was highly expressed in undifferentiated murine embryonic stem cells (ESCs). While the role of Mageb16 in stemness and differentiation of pluripotent...

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Published in:Sci Rep
Main Authors: Gaspar, John Antonydas, Srinivasan, Sureshkumar Perumal, Sureshkumar, Poornima, Doss, Michael Xavier, Hescheler, Jürgen, Papadopoulos, Symeon, Sachinidis, Agapios
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660239/
https://ncbi.nlm.nih.gov/pubmed/29079788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14561-z
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