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Oligomerization and ATP stimulate condensin-mediated DNA compaction
Large-scale chromatin remodeling during mitosis is catalyzed by a heteropentameric enzyme known as condensin. The DNA-organizing mechanism of condensin depends on the energy of ATP hydrolysis but how this activity specifically promotes proper compaction and segregation of chromosomes during mitosis...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5660149/ https://ncbi.nlm.nih.gov/pubmed/29079757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14701-5 |
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