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Oligomerization and ATP stimulate condensin-mediated DNA compaction

Large-scale chromatin remodeling during mitosis is catalyzed by a heteropentameric enzyme known as condensin. The DNA-organizing mechanism of condensin depends on the energy of ATP hydrolysis but how this activity specifically promotes proper compaction and segregation of chromosomes during mitosis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Keenholtz, Ross A., Dhanaraman, Thillaivillalan, Palou, Roger, Yu, Jia, D’Amours, Damien, Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660149/
https://ncbi.nlm.nih.gov/pubmed/29079757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14701-5
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