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The role of KRAB-ZFPs in transposable element repression and mammalian evolution

Kruppel-associated box zinc finger proteins (KRAB-ZFPs) make up the largest family of transcription factors in humans. These proteins emerged in the last common ancestor of coelacanth and tetrapods and have expanded and diversified in the mammalian lineage. Although their mechanism of transcriptiona...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: Yang, Peng, Wang, Yixuan, Macfarlan, Todd S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659910/
https://ncbi.nlm.nih.gov/pubmed/28935117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2017.08.006
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