Evolution of the mammalian transcription factor binding repertoire via transposable elements

Identification of lineage-specific innovations in genomic control elements is critical for understanding transcriptional regulatory networks and phenotypic heterogeneity. We analyzed, from an evolutionary perspective, the binding regions of seven mammalian transcription factors (ESR1, TP53, MYC, REL...

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Hlavní autoři: Bourque, Guillaume, Leong, Bernard, Vega, Vinsensius B., Chen, Xi, Lee, Yen Ling, Srinivasan, Kandhadayar G., Chew, Joon-Lin, Ruan, Yijun, Wei, Chia-Lin, Ng, Huck Hui, Liu, Edison T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
Letter
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577865/
https://ncbi.nlm.nih.gov/pubmed/18682548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.080663.108
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