INFLAMMATORY COLONIC INNATE LYMPHOID CELLS ARE INCREASED DURING UNTREATED HIV-1 INFECTION AND ASSOCIATED WITH MARKERS OF GUT DYSBIOSIS AND MUCOSAL IMMUNE ACTIVATION

BACKGROUND: HIV-1 infection is associated with intestinal inflammation, changes in the enteric microbiota (dysbiosis) and intestinal epithelial cell (IEC) damage. NKp44(+) innate lymphoid cells (ILCs) play an important role in epithelial barrier maintenance via the production of IL-22, but also disp...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Dillon, Stephanie M., Castleman, Moriah J., Frank, Daniel N., Austin, Gregory L, Gianella, Sara, Cogswell, Andrew C., Landay, Alan L., Barker, Edward, Wilson, Cara C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659896/
https://ncbi.nlm.nih.gov/pubmed/28825942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001523
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