Gut Dendritic Cell Activation Links an Altered Colonic Microbiome to Mucosal and Systemic T Cell Activation in Untreated HIV-1 infection

HIV-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. Dendritic cells (DCs) are crucial in maintaining intestinal homeostasis, but the impact of HIV-1 infection on intestinal DC number and function has not been extensively...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Dillon, SM, Lee, EJ, Kotter, CV, Austin, GL, Gianella, S, Siewe, B, Smith, DM, Landay, AL, McManus, MC, Robertson, CE, Frank, DN, McCarter, MD, Wilson, CC
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626441/
https://ncbi.nlm.nih.gov/pubmed/25921339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.33
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