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An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia

HIV-1 infection disrupts the intestinal immune system, leading to microbial translocation and systemic immune activation. We investigated the impact of HIV-1 infection on the intestinal microbiome and its association with mucosal T cell and dendritic cell (DC) frequency and activation, as well as wi...

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Detalhes bibliográficos
Main Authors: Dillon, SM, Lee, EJ, Kotter, CV, Austin, GL, Dong, Z, Hecht, DK, Gianella, S, Siewe, B, Smith, DM, Landay, AL, Robertson, CE, Frank, DN, Wilson, CC
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062575/
https://ncbi.nlm.nih.gov/pubmed/24399150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.116
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