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Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy

The heterogeneous nature of acute myeloid leukemia (AML) and its poor prognosis necessitate therapeutic improvement. Current advances in AML research yield important insights regarding AML genetic, epigenetic, evolutional, and clinical diversity, all in which dysfunctional p53 plays a key role. As p...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Prokocimer, Miron, Molchadsky, Alina, Rotter, Varda
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659817/
https://ncbi.nlm.nih.gov/pubmed/28607134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-763086
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