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Secretion of a recombinant protein without a signal peptide by the exocrine glands of transgenic rabbits

Transgenic rabbits carrying mammary gland specific gene constructs are extensively used for excreting recombinant proteins into the milk. Here, we report refined phenotyping of previously generated Venus transposon-carrying transgenic rabbits with particular emphasis on the secretion of the reporter...

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Vydáno v:PLoS One
Hlavní autoři: Kerekes, Andrea, Hoffmann, Orsolya Ivett, Iski, Gergely, Lipták, Nándor, Gócza, Elen, Kues, Wilfried A., Bősze, Zsuzsanna, Hiripi, László
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659788/
https://ncbi.nlm.nih.gov/pubmed/29077768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187214
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