Aldose Reductase Mediates NLRP3 Inflammasome–Initiated Innate Immune Response in Hyperglycemia-Induced Thp1 Monocytes and Male Mice

Despite recent studies that show oxidative stress–generated reactive oxygen species (ROS) regulate NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome–mediated innate immune response in various diabetic complications, the mechanism by which ROS activate innate immune response is...

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Publicado en:Endocrinology
Autores principales: Pal, Pabitra B., Sonowal, Himangshu, Shukla, Kirtikar, Srivastava, Satish K., Ramana, Kota V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659696/
https://ncbi.nlm.nih.gov/pubmed/28938395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00294
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