IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages

Aberrant proinflammatory and suppressed anti-inflammatory (alternative; M2) macrophage activation underlies the chronic inflammation associated with obesity and other metabolic disorders. This study demonstrates a critical role for interferon regulatory factor 6 (IRF6) in regulating macrophage M2 ac...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Li, Chuan, Ying, Wei, Huang, Zheping, Brehm, Tyler, Morin, Andrew, Vella, Anthony T., Zhou, Beiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659664/
https://ncbi.nlm.nih.gov/pubmed/28645193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00053
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