MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

Polarized activation of adipose tissue macrophages (ATMs) is crucial for maintaining adipose tissue function and mediating obesity-associated cardiovascular risk and metabolic abnormalities; however, the regulatory network of this key process is not well defined. Here, we identified a PPARγ/microRNA...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Ying, Wei, Tseng, Alexander, Chang, Richard Cheng-An, Morin, Andrew, Brehm, Tyler, Triff, Karen, Nair, Vijayalekshmi, Zhuang, Guoqing, Song, Hui, Kanameni, Srikanth, Wang, Haiqing, Golding, Michael C., Bazer, Fuller W., Chapkin, Robert S., Safe, Stephen, Zhou, Beiyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639972/
https://ncbi.nlm.nih.gov/pubmed/26436647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81656
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