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Protein dynamics and structural waters in bromodomains
Bromodomains are epigenetic readers of acetylated lysines that are integral parts of histone tails. The 61 bromodomains in humans are structurally highly conserved but specifically bind to widely varying recognition motifs, suggesting that dynamic rather than static factors are responsible for recog...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659604/ https://ncbi.nlm.nih.gov/pubmed/29077715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186570 |
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