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Protein dynamics and structural waters in bromodomains

Bromodomains are epigenetic readers of acetylated lysines that are integral parts of histone tails. The 61 bromodomains in humans are structurally highly conserved but specifically bind to widely varying recognition motifs, suggesting that dynamic rather than static factors are responsible for recog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Xiaoxiao, Chen, Kai, Wu, Yun-Dong, Wiest, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659604/
https://ncbi.nlm.nih.gov/pubmed/29077715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186570
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