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Beta-cells are not uniform after all – novel insights into molecular heterogeneity of insulin-secreting cells

While the beta-cells of the endocrine pancreas are defined as cells with high levels of insulin production and tight stimulus-secretion coupling, the existence of functional heterogeneity among them has been known for decades. Recent advances in molecular technologies, in particular single cell prof...

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Библиографические подробности
Опубликовано в: :Diabetes Obes Metab
Главные авторы: Avrahami, Dana, Wang, Yue J., Klochendler, Agnes, Dor, Yuval, Glaser, Benjamin, Kaestner, Klaus H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659199/
https://ncbi.nlm.nih.gov/pubmed/28880481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13019
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