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Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis

The molecular mechanisms underlying dysregulated wild type (wt) p53 in multiple myeloma (MM) have been subjects of intense investigation for years. Indeed, correlation of rarely occurring TP53 gene mutations or deletions with adverse clinical outcomes in MM patients is strongly established, while in...

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Bibliographische Detailangaben
Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Abdi, Jahangir, Rastgoo, Nasrin, Li, Lihong, Chen, Wenming, Chang, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659022/
https://ncbi.nlm.nih.gov/pubmed/29073933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0538-4
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