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Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis

The molecular mechanisms underlying dysregulated wild type (wt) p53 in multiple myeloma (MM) have been subjects of intense investigation for years. Indeed, correlation of rarely occurring TP53 gene mutations or deletions with adverse clinical outcomes in MM patients is strongly established, while in...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Abdi, Jahangir, Rastgoo, Nasrin, Li, Lihong, Chen, Wenming, Chang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659022/
https://ncbi.nlm.nih.gov/pubmed/29073933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0538-4
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