Enzymatic and Chemoenzymatic Three‐Step Cascades for the Synthesis of Stereochemically Complementary Trisubstituted Tetrahydroisoquinolines

Chemoenzymatic and enzymatic cascade reactions enable the synthesis of complex stereocomplementary 1,3,4‐trisubstituted tetrahydroisoquinolines (THIQs) with three chiral centers in a step‐efficient and selective manner without intermediate purification. The cascade employs inexpensive substrates (3‐...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Erdmann, Vanessa, Lichman, Benjamin R., Zhao, Jianxiong, Simon, Robert C., Kroutil, Wolfgang, Ward, John M., Hailes, Helen C., Rother, Dörte
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658969/
https://ncbi.nlm.nih.gov/pubmed/28727894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201705855
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados