Conformational Heterogeneity and FRET Data Interpretation for Dimensions of Unfolded Proteins

A mathematico-physically valid formulation is required to infer properties of disordered protein conformations from single-molecule Förster resonance energy transfer (smFRET). Conformational dimensions inferred by conventional approaches that presume a homogeneous conformational ensemble can be unph...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Song, Jianhui, Gomes, Gregory-Neal, Shi, Tongfei, Gradinaru, Claudiu C., Chan, Hue Sun
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2017
Materias:
Proteins
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658725/
https://ncbi.nlm.nih.gov/pubmed/28877485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.07.023
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