The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model

Neuronal network dysfunction and cognitive decline constitute the most prominent features of Alzheimer’s disease (AD), although mechanisms causing such impairments are yet to be determined. Here we report that virus-mediated delivery of the active spliced transcription factor X-Box binding protein 1...

Full description

Saved in:
Bibliographic Details
Published in:Mol Psychiatry
Main Authors: Cissé, M, Duplan, E, Lorivel, T, Dunys, J, Bauer, C, Meckler, X, Gerakis, Y, Lauritzen, I, Checler, F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658671/
https://ncbi.nlm.nih.gov/pubmed/27646263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.152
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items