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Parallel folding pathways of Fip35 WW domain explained by infrared spectra and their computer simulation

We present a calculation of the amide I’ infrared spectra of the folded, unfolded, and intermediate states of the WW domain Fip35, a model system for β-sheet folding. Using an all-atom molecular dynamics simulation in which multiple folding and unfolding events take place we identify six conformatio...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Zanetti-Polzi, Laura, Davis, Caitlin M., Gruebele, Martin, Dyer, R. Brian, Amadei, Andrea, Daidone, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658256/
https://ncbi.nlm.nih.gov/pubmed/28881468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12836
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