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Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing

Alpha herpesvirus genomes encode the capacity to establish quiescent infections (i.e. latency) in the peripheral nervous system for the life of their hosts. Multiple times during latency, viral genomes can reactivate to start a productive infection, enabling spread of progeny virions to other hosts....

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Koyuncu, Orkide O., MacGibeny, Margaret A., Hogue, Ian B., Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658187/
https://ncbi.nlm.nih.gov/pubmed/29073268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006608
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