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Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing

Alpha herpesvirus genomes encode the capacity to establish quiescent infections (i.e. latency) in the peripheral nervous system for the life of their hosts. Multiple times during latency, viral genomes can reactivate to start a productive infection, enabling spread of progeny virions to other hosts....

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書目詳細資料
發表在:PLoS Pathog
Main Authors: Koyuncu, Orkide O., MacGibeny, Margaret A., Hogue, Ian B., Enquist, Lynn W.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658187/
https://ncbi.nlm.nih.gov/pubmed/29073268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006608
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