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Comparison of multistate Markov modeling with contemporary outcomes in a reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial

Historically, ordinal measures of functional outcome have been dichotomized for the primary analysis in acute stroke therapy trials. A number of alternative methods to analyze the ordinal scales have been proposed, with an emphasis on maintaining the ordinal structure as much as possible. In additio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cassarly, Christy, Martin, Renee’ H., Chimowitz, Marc, Peña, Edsel A., Ramakrishnan, Viswanathan, Palesch, Yuko Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658159/
https://ncbi.nlm.nih.gov/pubmed/29073195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187050
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