Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis

Cold induced thermogenesis is an energy demanding process that protects endotherms against a reduction in ambient temperature. Using non-targeted LC-MS based lipidomics, we identified elevated levels of plasma acylcarnitines in response to the cold. We found that the liver undergoes a metabolic swit...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Metab
Main Authors: Simcox, Judith, Geoghegan, Gisela, Maschek, John Alan, Bensard, Claire L., Pasquali, Marzia, Miao, Ren, Lee, Sanghoon, Jiang, Lei, Huck, Ian, Kershaw, Erin E., Donato, Anthony J., Apte, Udayan, Longo, Nicola, Rutter, Jared, Schreiber, Renate, Zechner, Rudolf, Cox, James, Villanueva, Claudio J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658052/
https://ncbi.nlm.nih.gov/pubmed/28877455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.08.006
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